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Fast Fact and Concept #133
Non-Oral Hydration in Palliative Care

Author(s): Robin Fainsinger

At the center of the debate with regard to hydration in terminally ill patients is the desire to maintain comfort and avoid unnecessary/distressing procedures. There is no controversy that terminally ill patients should be encouraged to maintain adequate oral hydration for as long as possible. However there is debate and controversy around the use of parenteral hydration.

Arguments Against Hydration

bulletcomatose patients do not experience symptom distress
bulletparenteral fluids may prolong dying
bulletwith less urine there is less need to void and use catheters
bulletwith less gastrointestinal fluid there can be less nausea and vomiting
bulletwith less respiratory tract secretions there can be less cough and pulmonary edema
bulletdehydration can help reduce distressing edema or ascites
bulletdehydration may be a “natural” anesthetic to ease the dying process
bulletparenteral hydration can be uncomfortable (e.g. needles/catheters) and limit patient mobility

Arguments For Hydration

bulletdehydration can lead to pre-renal azotemia, which in turn can lead to accumulation of drug metabolites (notably opioids), leading to delirium, myoclonus and seizures. Hydration can reverse these symptoms in some patients leading to improved comfort
bulletthere is no evidence that fluids prolong the dying process
bulletproviding hydration can maintain the appearance of “doing something”, even though there may be no medical value, and thus ease family anxiety around the time of death

Ethical/Legal Issues

In the United States, the following ethical/legal standards exist:

bulletCompetent patients or their surrogate decision-makers can accept or refuse hydration based on relevant information.
bulletNon-oral hydration is considered a medical intervention, not ordinary care--as such, there is no legal or ethical imperative to provide a medical intervention unless the benefits outweigh the burdens.

Recommendation

There is research literature to support both the use of, and withholding of, non-oral hydration in patients near death; thus, there is no consensus on the single best approach to care. Key issues to be considered when determining the role of non-oral hydration include the following:

bulletExpressed wishes of the patient or surrogate decision-maker regarding use of hydration;
bulletPatient-defined goals; the presence of a specific goal may direct the clinician to use hydration as a means to improve delirium and potentially delay death;
bulletSymptom burden: symptoms related to total body water excess may improve by withholding hydration, while delirium may lessen with hydration;
bulletBurden to the patient and caregivers of maintaining the non-oral route of hydration;
bulletFamily distress concerning withholding hydration/nutrition;
bulletWhen in doubt, a time limited hydration trial is an appropriate recommendation.

Finally, it is important to recognize that health care providers often have biases for or against non-oral hydration near the end-of- life—self-reflection upon these biases is crucial to help patients and families make decisions that are based on the best interests and goals of the patient/family unit.

References

Fainsinger RL. Hydration. In: Ripamonti C; Bruera E. Editors. Gastrointestinal Symptoms in Advanced Cancer Patients. Oxford University Press, 2002: 395-410.

MacDonald N. Ethical considerations in feeding or hydrating advanced cancer patients. In: Ripamonti C; Bruera E. Editors. Gastrointestinal Symptoms in Advanced Cancer Patients. Oxford University Press, 2002: 411-423.

Lawlor PG. Delirium and dehydration: Some fluid for thought? Support Care Cancer 2002; 10:445-454.

Sarhill N, Walsh D, Nelson K, Davies M. Evaluation and treatment of cancer related fluid deficits: Volume depletion and dehydration. Support Care Cancer 2001; 9:408-419.

Copyright/Referencing Information : Users are free to download and distribute Fast Facts for educational purposes only. Citation for referencing: Fainsinger R . Non-oral hydration in palliative care. Fast Facts and Concepts #132: April 2005. End-of-Life Physician Education Resource Center www.eperc.mcw.edu.

Disclaimer: Fast Facts provide educational information, this information is not medical advice. Health care providers should exercise their own independent clinical judgment. Some Fast Fact information cites the use of a product in dosage, for an indication, or in a manner other than that recommended in the product labeling. Accordingly, the official prescribing information should be consulted before any such product is used.

Creation Date: 3/2005

Purpose: Self-Study Guide, Teaching

Audience(s)

     Training: Fellows, 3rd/4th Year Medical Students, PGY1 (Interns), PGY2-6, Physicians in Practice
     Specialty: Anesthesiology, Emergency Medicine, Family Medicine, General Internal Medicine, Geriatrics, Hematology/Oncology, Neurology, OB/GYN, Ophthalmology, Pulmonary/Critical Care, Pediatrics, Psychiatry, Surgery
     Non-Physician: Nurses


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Last modified: May 04, 2008