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Neonatal Care

 

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Newborn Autopsy

   Last Updated: March 25, 2008

New Additions
 
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Pregnancy and Palliative Care
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Perinatal hospices support families with a terminal prenatal diagnosis

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Watch the video

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"Pregnancy care: an apprenticeship for Palliative Care?"

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Disagreement between parents and health professionals regarding pain intensity in critically ill neonates

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Neonatal pain treatment: ethical to be effective

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Long-term consequences of early infant injury and trauma upon somatosensory processing

 

Prior Additions
 
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Safety profile of morphine following surgery in neonates

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Breastfeeding or breastmilk to alleviate procedural pain in neonates: a systematic review

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Effects of Midazolam and Morphine on Cerebral Oxygenation and Hemodynamics in Ventilated Premature Infants

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Cortical pain responses in the infant brain

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State of the science: procedural pain management in the neonate

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Another Breastfeeding Benefit: Pain Reliever for Newborns

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Consistent management of repeated procedural pain with sucrose in preterm neonates: Is it effective and safe for repeated use over time?

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Study shows premature babies can feel pain

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Summary Proceedings From the Neonatal Pain-Control Group

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Tetracaine May Be Helpful for Analgesia in Neonates (requires Medscape login)

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Fetal pain: a systematic multidisciplinary review of the evidence

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Pain reactivity in 2-month-old infants after prenatal and postnatal serotonin reuptake inhibitor medication exposure

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The reliability and validity of the COMFORT scale as a postoperative pain instrument in 0 to 3-year-old infants

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Morphine Does Not Provide Adequate Analgesia for Acute Procedural Pain Among Preterm Neonates

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Childhood Pain May Play Part In Chronic Adult Issues

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Oral hypertonic glucose spray: a practical alternative for analgesia in the newborn

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Sedatives for opiate withdrawal in newborn infants

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Specific Newborn Individualized Developmental Care and Assessment Program
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Movements are associated with acute pain in preterm infants in the neonatal intensive care unit

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NPAS - Neonatal Pain, Agitation, and Sedation Scale
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The N-PASS is a valid and reliable clinical pain/agitation and sedation tool for neonates. Nurses find the N-PASS easy and quick to use clinically, facilitating documentation and management of pain and sedation.

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Parental concern and distress about infant pain
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Conclusions: Parents have unmet information needs about infant pain and wish greater involvement in their infant’s pain care. Parent concerns about infant pain may contribute to parental stress.

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Prevention and management of pain and stress in the neonate
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Guideline from National Guideline Clearinghouse

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Consensus Statement on Neonatal Pain

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Neonatal Pain: The Evolution of an Idea

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Randomized trial of analgesic effects of sucrose, glucose, and pacifiers in term neonates
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Both sucrose solution and the sucking reflex act to relieve pain in newborns.

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EMLA Cream for Circumcision

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Effect of neonatal circumcision on pain responses during vaccination in boys

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Bladder Retention of Urine as a Result of Continuous Intravenous Infusion of Fentanyl: 2 Case Reports

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A Pictorial and Video Guide to Circumcision Without Pain
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This is a superbly presented, thorough discussion of the topic. You may need to login on Medscape and search for ID #: 453637

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Their suggestion: "Using a multimodal approach to pain prevention during a newborn circumcision might lead to the following approach. The infant is premedicated with a 10- to 15-mg/kg dose of acetaminophen by mouth at least 30 minutes before the procedure. He is placed on a padded circumcision chair with his legs restrained in a comfortable, semiflexed position. His arms are secured with a swaddled blanket technique and placed in a flexed position with his hands placed near his face to allow for self-comforting measures. He is under a radiant warmer so his temperature is consistent and comfortable. His eyes are shielded from any bright light. A pacifier along with some 25% sucrose water is provided. His penis and groin are prepped with a warmed anti-septic solution, and 0.5% or 1% lidocaine is administered slowly in an SQRB (Fig 9). The circumcision is performed with a Mogen clamp. When the circumcision is complete, the infant is given to his parents, who will comfort and cuddle him, and he receives additional oral doses of acetaminophen every 6 to 8 hours, for 24 hours."

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Oral Glucose is Better than EMLA

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Age- and therapy-related effects on morphine requirements and plasma concentrations of morphine and its metabolites in postoperative infants

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Repeated neonatal pain influences maternal behavior, but not stress responsiveness in rat offspring
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These results suggest that repeated pain during the first 2 weeks of life in the rat does not lead to significant changes in stress responsiveness in 2-week-old pups, but we suggest that changes in mother-pup interaction (increased grooming) might act as a buffer on the cumulative effect of pain on stress responsiveness.

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Crying of a newborn child: alarm signal or protocommunication? Percept Mot Skills 2002 Dec;95:752-4

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In praise of the epidural space for analgesia in neonates Paediatr Anaesth 2002 Nov;12(9):836-7

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Effect of postpartum anxiety on the colostral milk beta-endorphin concentrations of breastfeeding mothers
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These data indicate that the labour pain and the vaginal delivery process play a central role in increasing colostral opioid availability for the breastfed neonate; peripartal maternal anxiety is a negative psychobiological determinant in opioid galactopoiesis, and possibly in the postnatal development of several related biological functions of growing infants.

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Major Surgery Within the First 3 Months of Life and Subsequent Biobehavioral Pain Responses to Immunization at Later Age: A Case Comparison Study
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Conclusions. Major surgery in combination with preemptive analgesia within the first months of life does not alter pain response to subsequent pain exposure in childhood. Greater exposure to early hospitalization influences the pain responses after prolonged time. These responses, however, diminish after a prolonged period of nonexposure.

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Prevention and management of pain and stress in the neonate - National Guideline Review

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Prevention and management of pain and stress in the neonate - AAP Policy (pdf)

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Consensus Statement on Neonatal Pain - International Evidence-Based Group for Neonatal Pain (pdf)

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Low-dose Morphine Does Not Cause Neurological Injury in Preterm Infants (pdf)

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Breastfeeding Is Analgesic in Healthy Newborns (pdf)

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Neonatal Pain: The Evolution of an Idea

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Randomized trial of analgesic effects of sucrose, glucose, and pacifiers in term neonates
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Both sucrose solution and the sucking reflex act to relieve pain in newborns.

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EMLA Cream for Circumcision

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Effect of neonatal circumcision on pain responses during vaccination in boys

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Neonatal Pain Management (an early review)

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Bladder Retention of Urine as a Result of Continuous Intravenous Infusion of Fentanyl: 2 Case Reports


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Last modified: May 04, 2008