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Morphine: A Comfort Measure For The
Dying Or Pain Control For The Living? |
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FDA Issues Second
Safety Warning on Fentanyl Skin Patch |
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Randomized clinical
trial of nebulized fentanyl citrate versus i.v. fentanyl citrate in
children presenting to the emergency department with acute pain |
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Oral Oxymorphone for
Pain Management |
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FAST FACT AND CONCEPT #175: Opioid Allergic Reactions |
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Opioid use and survival at the end of life: a survey of a
hospice population |
 |
Toward evidence-based prescribing at end of life: a
comparative analysis of sustained-release morphine, oxycodone, and
transdermal fentanyl, with pain, constipation, and caregiver interaction
outcomes in hospice patients |
 |
"Broken heart syndrome" after separation (from OxyContin) |
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Opioids for Chronic Non-Cancer Pain |
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Fentanyl
transdermal patch is an effective way to control pain in children |
 |
Patient-controlled analgesia: optimizing the experience |
 |
Age-related postoperative morphine requirements in children following
major surgery--an assessment using patient-controlled analgesia (PCA) |
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Morphine consumption and respiratory depression in children receiving
postoperative analgesia from continuous morphine infusion or patient
controlled analgesia |
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A double-blind comparison of morphine infusion and patient controlled
analgesia in children |
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Pediatric patient-controlled analgesia: enhancing the self-care
construct |
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Intravenous morphine at 0.1 mg/kg is not effective for controlling
severe acute pain in the majority of patients |
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New Fentanyl Warnings: More Needed to Protect Patients
 |
from Medscape -- this will require a login (or free
registration) |
|
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Tramadol SR Formulations: Pharmacokinetic Comparison of a Multiple-Units
Dose (Capsule) versus a Single-Unit Dose (Tablet)
 |
from Medscape -- this will require a login (or free
registration) |
|
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Methadone as an analgesic for cancer pain management |
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Retrospective analysis of kadian (morphine sulfate sustained-release
capsules) in patients with chronic, nonmalignant pain |
 |
Morphine sparing with droperidol in patient-controlled analgesia |
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Pharmacologic Treatment of Opioid-Induced Sedation in Chronic Pain |
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Tramadol Exposures Reported to Statewide Poison Control System |
 |
The effects of a small-dose naloxone infusion on opioid-induced side
effects and analgesia in children and adolescents treated with
intravenous patient-controlled analgesia |
 |
Treatment of noncancer pain with oral transmucosal fentanyl citrate (OTFC)
(from Pain.com) |
 |
Two Formulations
of Extended-Release Oral Morphine Reach Similar Plasma Levels |
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Peripheral opioids in inflammatory pain |
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Enteral administration of naloxone for treatment of opioid-associated
intragastric feeding intolerance |
 |
Continuous Subcutaneous Infusion of Opiates at End-of-Life |
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The bioavailability of morphine applied topically to cutaneous ulcers |
 |
Incidence of constipation associated with long-acting opioid therapy: a
comparative study |
 |
Developmental pharmacokinetics of morphine and its metabolites in
neonates, infants and young children |
 |
Addition of ultralow dose naloxone to postoperative morphine PCA:
unchanged analgesia and opioid requirement but decreased incidence of
opioid side effects |
 |
New Formulation Of Actiq (Oral Transmucosal Fentanyl Citrate) Approved
By FDA |
 |
New Perspectives on the Pharmacology of Opioids and Their Use in Chronic
Pain (CME Available) |
 |
Optimizing Analgesic Response When Pain is Uncontrolled by Oral Opioids
 |
This article is from
Cancer Pain Release, where you can find many other similar review
articles |
|
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Opioids in cancer pain: common dosing errors |
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The importance of
opioid tolerance: a therapeutic paradox J.Amer Coll Surg.
Feb. 2003. Vol. 196, No.2:321-4. |
 |
Characteristics and adequacy of intravenous morphine infusions in
children in a paediatric oncology setting |
 |
Oral tramadol for the treatment of pain of 7-30 days' duration in
children
 |
This open-label, multicenter
trial was designed to determine the safety profile and analgesic
efficacy of tramadol for the treatment of painful conditions lasting
7-30 days in 7-16-yr-old children. We found that tramadol 1-2 mg/kg per
os every 4-6 h (maximal dose = 8 mg x kg(-1). d(-1), not to exceed 400
mg/d) is a safe and effective analgesic in this patient population. |
|
 |
Clinical pharmacology of opioids for pain
 |
Inturrisi CE. Clin J Pain
2002 Jul-Aug;18(4 Suppl):S3-13
Department of Pharmacology, Weill Medical College of Cornell
University, Pain and Palliative Care Service, Memorial Sloan-Kettering
Cancer Center, New York, New York 10021, USA |
|
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Effects of intermediate- and long-term use of opioids on cognition in
patients with chronic pain
 |
"Relatively few differences have been found when
cognitive performance in these patients is compared with their
performance before taking opioids, or with the performance of a
comparable pain population not taking opioids. Major unresolved
questions remain regarding such important issues as effects of
different types of opioids, dose effects, interactions with other
medications, and subject variables." |
|
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FDA Approves Once-Daily Avinza (Extended Release Morphine) For Chronic,
Moderate-To-Severe Pain |
 |
EPERC Fast Fact and Concept
#75: Methadone for Pain |
 |
Einstein Researchers Report on Safer Narcotic Painkillers That Prevent
Dependency, Withdrawal Problems |
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PRN Range for Analgesic Orders |
 |
Sufentanil:
an overview of its use for acute pain management |
 |
Strategies to manage the adverse effects of oral morphine: an
evidence-based report |
 |
Intravenous Methadone in the Management of Chronic Cancer Pain |
 |
Pioneering Durogesic (Transdermal Fentanyl) Skin Patch:
A Clear Choice In
Chronic Pain Which Is Difficult To Treat
 |
May 27, 2002 -- The UK's
first skin patch to offer strong pain relief (DurogesicTM - transdermal
fentanyl) - has received approval from UK regulators allowing its use
for the first time to treat chronic (ongoing or continued) intractable
pain such as arthritis and back pain. |
|
 |
Reducing Morphine
Tolerance (pdf) |
 |
An
Individual Opinion on the Use of Demerol for Rigors |
 |
Nasal
Diamorphine Preferred For Children With Limb Fractures
 |
Seems like
a great idea: 0.1 mg/kg diamorphine intranasally relieves severe
fracture pain faster that an IM injection without the need for a
needle. This study was performed in Great Britain. Hopefully the
product will become available in the United States. This is a
review of the article in the British Med Journal, with a
link to the full text version. |
|
 |
The
Neurotoxicity of Opioids
 |
This is a
brief case presentation demonstrating some of the common side effects
of opioid analgesics and their management. |
|
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Methadone in
the Treatment of Chronic Non-Malignant Pain-a 2-Year Review
 |
We are
re-learning the benefits of methadone. Consider this medication in
the treatment of post-herpetic neuralgia. This
is a review of the article in Pain Medicine and a link to its
abstract. |
|