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General
Review
Last Updated:
February 22, 2008
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Assessment
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Complimentary Interventions
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Complex Regional Pain Syndrome
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Common
anesthetic drug found effective in treating severe CRPS pain |
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Reflex sympathetic dystrophy/complex regional pain syndrome clinical
practice guidelines - third edition |
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Neurotropin Research Study |
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RSD
Research from Reflex Sympathetic Dystrophy Syndrome Association |
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RSD
Treatment from Reflex Sympathetic Dystrophy Syndrome Association |
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Clinical Guidelines from
Reflex Sympathetic Dystrophy Syndrome Association |
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Spinal cord stimulation in complex regional pain syndrome: cervical and
lumbar devices are comparably effective |
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Clinical practice guideline (second edition) for the diagnosis,
treatment, and management of reflex sympathetic dystrophy/complex
regional pain syndrome (RSD/CRPS)
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Case Series: IV Regional Anesthesia with Ketorolac and Lidocaine: Is
It Effective for the Management of Complex Regional Pain Syndrome 1 in
Children and Adolescents? |
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Complex regional pain syndrome - diagnostic, mechanisms, CNS involvement
and therapy |
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Complex regional pain syndrome and lyme borreliosis: two different
diseases?
 | Complex regional pain syndrome (CRPS) is a frequent
complication appearing as pain of unexplained pathogenesis. Its
association with Lyme borreliosis (LB) is fairly rare. In the
presented clinical case,...the patient fulfilled the criteria for both
diagnoses, i.e. CRPS and LB. The subsequent antibiotic therapy
resulted in a complete remission of both clinical entities. |
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| Neurostimulation Found More Effective and Less
Expensive Than Standard Treatment Protocol for Chronic Reflex
Sympathetic Dystrophy
| An important financial assessment of
neurostimulation was recently published in the journal, Neurology by
Marius A. Kemler, MD Ph.D and Carina A. Furnée, Ph.D . (Neurology
2002;59:1203-1209). Available by order from the
Chronic Pain Resource
Center. |
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| New Studies Available on the Cost-Effectiveness of
Neurostimulation and Intrathecal Drug Delivery
| Two recent journal articles by Krishna Kumar, M.B.,
M.S. FRCS(C), F.A.C.S. compare the cost-effectiveness of both
neurostimulation and intrathecal drug delivery vs. conventional pain
therapies in patients with failed back syndrome. Neurostimulation and
intrathecal drug delivery were found to be cost-effective in the
long-term, despite initial costs of the implantable devices. The
neurostimulation article is available to order through "journal
reprints" section of the web site (Neurosurgery; 51:106-116, 2002).
Available by order from the
Chronic Pain Resource
Center. |
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Fibromyalgia
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Headache
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Antiepileptic Drug Keppra (Levetiracetam) Reduces Migraine Pain in
Children |
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Topiramate in the prophylactic treatment of migraine in children |
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Butterbur for Migraine Prevention |
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Headstrong: A Pilot Study of a CD-ROM Intervention for Recurrent
Pediatric Headache |
| The efficacy and
safety of venlafaxine in the prophylaxis of migraine |
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Surgery Can Reduces Migraine Symptoms |
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Topiramate in migraine prophylaxis: a randomised double-blind versus
placebo study |
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American Academy of Neurology Issues Guidelines for Pediatric Migraine |
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Surgical treatment of migraines reduces sick days and increases employee
productivity |
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Anticonvulsants in migraine |
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Flunarizine in prophylaxis of childhood migraine. A double-blind,
placebo-controlled, crossover study |
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Prophylactic migraine therapy: emerging treatment options |
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Electroacupuncture for Tension-type Headache on Distal Acupoints Only: A
Randomized, Controlled, Crossover Trial |
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Patients Who Responded Poorly to Excedrin-Migraine May Get Significant
Pain Relief With Relpax (Eletriptan) |
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Acupuncture in Addition to Standard Care Confers Clinical Benefit to
Patients with Chronic Headache |
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Strict bed rest following lumbar puncture in children and adolescents is
of no benefit
| Another medical myth is on its way out |
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Topiramate for migraine prevention: a randomized controlled trial |
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Efficacy of topiramate in migraine aura prophylaxis: preliminary results
of 12 patients |
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Botulinum toxin and other new approaches to migraine therapy |
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Brain imaging and prophylactic therapy in children with migraine:
recommendations versus reality
| Conclusions: Imaging is more frequently obtained
and prophylactic therapy less frequently implemented by the referring
physician than would be indicated by published recommendations. |
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Divalproex Sodium Decreases Headaches by Half |
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Triptans May Be Ineffective in Migraine With Cutaneous Allodynia CME
(you will need to login at Medscape) |
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Review of Recent Advances in Acute Migraine Treatment and Prevention |
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Pathogenesis of the migraine attack |
| Frovatriptan |
| Eye-Strain Headache |
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The Usefulness
of Children's Drawings in the Diagnosis of Headache (pdf) |
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Antiepileptic Drugs for Migraine Prophylaxis (pdf) |
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Frequent Headache: A Far Too Common Problem (pdf) |
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Migraine, Tension-Type Headaches, and Their Combination Effects on
Health Outcomes, Quality of Life, and Productivity (pdf) |
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Once-Daily, Extended-Release Divalproex Sodium for Migraine Headache
Prophylaxis: A Study of Safety and Efficacy (pdf) |
| GABA
Receptors Appear to Modulate Nociceptive Transmission in the
Trigeminocervical Complex (pdf) |
| Botox
Effective in Headache Pain Relief |
| Prophylactic
treatment of migraine with angiotensin converting enzyme inhibitor
(lisinopril): randomized, placebo controlled, crossover study
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Add this
option to your list of effective migraine prevention strategies. |
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Efficacy
and Safety of Acetaminophen in the Treatment of Migraine
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Acute Treatment Strategies for Migraine |
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Local Control Measures
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Narcotics
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Pharmacologic Treatment of Opioid-Induced Sedation in Chronic Pain |
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Tramadol Exposures Reported to Statewide Poison Control System |
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The effects of a small-dose naloxone infusion on opioid-induced side
effects and analgesia in children and adolescents treated with
intravenous patient-controlled analgesia |
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Treatment of noncancer pain with oral transmucosal fentanyl citrate (OTFC)
(from Pain.com) |
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Two Formulations
of Extended-Release Oral Morphine Reach Similar Plasma Levels |
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Peripheral opioids in inflammatory pain |
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Enteral administration of naloxone for treatment of opioid-associated
intragastric feeding intolerance |
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Continuous Subcutaneous Infusion of Opiates at End-of-Life |
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The bioavailability of morphine applied topically to cutaneous ulcers |
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Incidence of constipation associated with long-acting opioid therapy: a
comparative study |
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Developmental pharmacokinetics of morphine and its metabolites in
neonates, infants and young children |
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Addition of ultralow dose naloxone to postoperative morphine PCA:
unchanged analgesia and opioid requirement but decreased incidence of
opioid side effects |
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New Formulation Of Actiq (Oral Transmucosal Fentanyl Citrate) Approved
By FDA |
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New Perspectives on the Pharmacology of Opioids and Their Use in Chronic
Pain (CME Available) |
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Optimizing Analgesic Response When Pain is Uncontrolled by Oral Opioids
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This article is from
Cancer Pain Release, where you can find many other similar review
articles |
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Opioids in cancer pain: common dosing errors |
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The importance of
opioid tolerance: a therapeutic paradox J.Amer Coll Surg.
Feb. 2003. Vol. 196, No.2:321-4. |
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Characteristics and adequacy of intravenous morphine infusions in
children in a paediatric oncology setting |
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Oral tramadol for the treatment of pain of 7-30 days' duration in
children
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This open-label, multicenter
trial was designed to determine the safety profile and analgesic
efficacy of tramadol for the treatment of painful conditions lasting
7-30 days in 7-16-yr-old children. We found that tramadol 1-2 mg/kg per
os every 4-6 h (maximal dose = 8 mg x kg(-1). d(-1), not to exceed 400
mg/d) is a safe and effective analgesic in this patient population. |
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Clinical pharmacology of opioids for pain
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Inturrisi CE. Clin J Pain
2002 Jul-Aug;18(4 Suppl):S3-13
Department of Pharmacology, Weill Medical College of Cornell
University, Pain and Palliative Care Service, Memorial Sloan-Kettering
Cancer Center, New York, New York 10021, USA |
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Effects of intermediate- and long-term use of opioids on cognition in
patients with chronic pain
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"Relatively few differences have been found when
cognitive performance in these patients is compared with their
performance before taking opioids, or with the performance of a
comparable pain population not taking opioids. Major unresolved
questions remain regarding such important issues as effects of
different types of opioids, dose effects, interactions with other
medications, and subject variables." |
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FDA Approves Once-Daily Avinza (Extended Release Morphine) For Chronic,
Moderate-To-Severe Pain |
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EPERC Fast Fact and Concept
#75: Methadone for Pain |
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Einstein Researchers Report on Safer Narcotic Painkillers That Prevent
Dependency, Withdrawal Problems |
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PRN Range for Analgesic Orders |
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Sufentanil:
an overview of its use for acute pain management |
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Strategies to manage the adverse effects of oral morphine: an
evidence-based report |
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Intravenous Methadone in the Management of Chronic Cancer Pain |
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Pioneering Durogesic (Transdermal Fentanyl) Skin Patch:
A Clear Choice In
Chronic Pain Which Is Difficult To Treat
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May 27, 2002 -- The UK's
first skin patch to offer strong pain relief (DurogesicTM - transdermal
fentanyl) - has received approval from UK regulators allowing its use
for the first time to treat chronic (ongoing or continued) intractable
pain such as arthritis and back pain. |
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Reducing Morphine
Tolerance (pdf) |
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An
Individual Opinion on the Use of Demerol for Rigors |
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Nasal
Diamorphine Preferred For Children With Limb Fractures
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Seems like
a great idea: 0.1 mg/kg diamorphine intranasally relieves severe
fracture pain faster that an IM injection without the need for a
needle. This study was performed in Great Britain. Hopefully the
product will become available in the United States. This is a
review of the article in the British Med Journal, with a
link to the full text version. |
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The
Neurotoxicity of Opioids
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This is a
brief case presentation demonstrating some of the common side effects
of opioid analgesics and their management. |
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Methadone in
the Treatment of Chronic Non-Malignant Pain-a 2-Year Review
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We are
re-learning the benefits of methadone. Consider this medication in
the treatment of post-herpetic neuralgia. This
is a review of the article in Pain Medicine and a link to its
abstract. |
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Neonatal
Issues
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